Muscle-invasive Bladder Cancer in the Elderly Patient With a Focus on Hypofractionated Radiotherapy

Abstract Muscle-invasive bladder cancer is most frequently diagnosed in older patients and the presence of multimorbidity frailty common. This means that many are unsuitable for definitive treatment with radical cystectomy/(chemo)radiotherapy at risk poor survival outcomes considerable disease-related morbidity. Screening tools functional status may be useful to determine appropriate an person identify likely benefit from comprehensive geriatric assessment its targeted prehabilitation interventions. For treatment, ultrahypofractionated radiotherapy schedules provide good local control acceptable toxicity. Short fractionated palliative can effective symptom longer courses treatment.